Reduced Insulin Signaling Targeted to Serotonergic Neurons but Not Other Neuronal Subtypes Extends Lifespan in Drosophila melanogaster

Reduced Insulin/IGF-like signaling (IIS) plays an evolutionarily conserved role in improving longevity and some measures of health-span in model organisms. Recent studies, however, have found a disconnection between lifespan extension and behavioral health-span. We have previously shown that reducti...

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Detalles Bibliográficos
Autores principales: Dravecz, Nikolett, Shaw, Tommy, Davies, Isabella, Brown, Casey, Ormerod, Lewis, Vu, Gin, Walker, Tyler, Taank, Taran, Shirras, Alan D., Broughton, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294736/
https://www.ncbi.nlm.nih.gov/pubmed/35865744
http://dx.doi.org/10.3389/fnagi.2022.893444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294736/
https://www.ncbi.nlm.nih.gov/pubmed/35865744
http://dx.doi.org/10.3389/fnagi.2022.893444

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