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Docking-Based Virtual Screening Enables Prioritizing Protein Kinase Inhibitors With In Vitro Phenotypic Activity Against Schistosoma mansoni

Schistosomiasis is a parasitic neglected disease with praziquantel (PZQ) utilized as the main drug for treatment, despite its low effectiveness against early stages of the worm. To aid in the search for new drugs to tackle schistosomiasis, computer-aided drug design has been proved a helpful tool to...

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Detalles Bibliográficos
Autores principales: Moreira, Bernardo Pereira, Batista, Izabella Cristina Andrade, Tavares, Naiara Clemente, Armstrong, Tom, Gava, Sandra Grossi, Torres, Gabriella Parreiras, Mourão, Marina Moraes, Falcone, Franco H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294739/
https://www.ncbi.nlm.nih.gov/pubmed/35865824
http://dx.doi.org/10.3389/fcimb.2022.913301

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