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Docking-Based Virtual Screening Enables Prioritizing Protein Kinase Inhibitors With In Vitro Phenotypic Activity Against Schistosoma mansoni
Schistosomiasis is a parasitic neglected disease with praziquantel (PZQ) utilized as the main drug for treatment, despite its low effectiveness against early stages of the worm. To aid in the search for new drugs to tackle schistosomiasis, computer-aided drug design has been proved a helpful tool to...
Autores principales: | Moreira, Bernardo Pereira, Batista, Izabella Cristina Andrade, Tavares, Naiara Clemente, Armstrong, Tom, Gava, Sandra Grossi, Torres, Gabriella Parreiras, Mourão, Marina Moraes, Falcone, Franco H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294739/ https://www.ncbi.nlm.nih.gov/pubmed/35865824 http://dx.doi.org/10.3389/fcimb.2022.913301 |
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