Improvement of macrolactins production by the genetic adaptation of Bacillus siamensis A72 to saline stress via adaptive laboratory evolution

BACKGROUND: Macrolactins, a type of macrolide antibiotic, are toxic to the producer strains. As such, its level is usually maintained below the lethal concentration during the fermentation process. To improve the production of macrolactins, we applied adaptive laboratory evolution technology to engi...

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Detalles Bibliográficos
Autores principales: Gan, Yuman, Bai, Meng, Lin, Xiao, Liu, Kai, Huang, Bingyao, Jiang, Xiaodong, Liu, Yonghong, Gao, Chenghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294813/
https://www.ncbi.nlm.nih.gov/pubmed/35854349
http://dx.doi.org/10.1186/s12934-022-01871-9

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