Lithocholic acid inhibits dendritic cell activation by reducing intracellular glutathione via TGR5 signaling

Dendritic cells (DCs) are the major antigen-presenting cells and play an important role in autoimmune uveitis. Emerging evidence suggests that bile acids (BAs) regulate DCs maturation. However, the underlying mechanisms by which BAs regulate the function of DCs still need to be clarified. Here, we d...

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Detalles Bibliográficos
Autores principales: Hu, Jianping, Zhang, Yiting, Yi, Shenglan, Wang, Chaokui, Huang, Xinyue, Pan, Su, Yang, Jinglu, Yuan, Gangxiang, Tan, Sisi, Li, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295063/
https://www.ncbi.nlm.nih.gov/pubmed/35864954
http://dx.doi.org/10.7150/ijbs.71287

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