Smoke-induced SAV1 Gene Promoter Hypermethylation Disrupts YAP Negative Feedback and Promotes Malignant Progression of Non-small Cell Lung Cancer

YAP (gene symbol YAP1) as a potential oncoprotein, is positively correlated with the malignancy of various tumors. However, overexpression of YAP alone in multiple normal tissue cells has failed to induce tumor formation and the underlying mechanism is poorly understood. Herein, we show that YAP act...

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Detalles Bibliográficos
Autores principales: Liu, Ting, Guo, Wei, Luo, Kai, Li, Lei, Dong, Jing, Liu, Meijun, Shi, Xingyuan, Wang, Zhiyuan, Zhang, Jianlei, Yin, Jiang, Qiu, Ni, Lu, Minying, Chen, Danyang, Jia, Xiaoting, Liu, Hao, Gu, Yixue, Xiong, Yan, Zheng, Guopei, Xu, Gang, He, Zhimin, Zhang, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295071/
https://www.ncbi.nlm.nih.gov/pubmed/35864957
http://dx.doi.org/10.7150/ijbs.73428

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