Multiparametric High-Content Cell Painting Identifies Copper Ionophores as Selective Modulators of Esophageal Cancer Phenotypes

[Image: see text] Esophageal adenocarcinoma is of increasing global concern due to increasing incidence, a lack of effective treatments, and poor prognosis. Therapeutic target discovery and clinical trials have been hindered by the heterogeneity of the disease, the lack of “druggable” driver mutatio...

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Detalles Bibliográficos
Autores principales: Hughes, Rebecca E., Elliott, Richard J. R., Li, Xiaodun, Munro, Alison F., Makda, Ashraff, Carter, Roderick N., Morton, Nicholas M., Fujihara, Kenji, Clemons, Nicholas J., Fitzgerald, Rebecca, O’Neill, J. Robert, Hupp, Ted, Carragher, Neil O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295120/
https://www.ncbi.nlm.nih.gov/pubmed/35696676
http://dx.doi.org/10.1021/acschembio.2c00301

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