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Introducing SuFNucs: Sulfamoyl-Fluoride-Functionalized Nucleosides That Undergo Sulfur Fluoride Exchange Reaction

[Image: see text] The reaction between ribonucleosides and ex situ generated sulfonyl fluoride has been developed. The reaction takes place at the −NH(2) groups of nucleobases, and the resulting nucleosides are equipped with a sulfamoyl fluoride moiety, dubbed SuFNucs. These species undergo a select...

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Detalles Bibliográficos
Autores principales: Chrominski, Mikołaj, Ziemkiewicz, Kamil, Kowalska, Joanna, Jemielity, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295159/
https://www.ncbi.nlm.nih.gov/pubmed/35771144
http://dx.doi.org/10.1021/acs.orglett.2c02034