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Fetal congenital heart disease - mode of delivery and obstetrical complications

BACKGROUND: The optimal mode of delivery in cases of fetal congenital heart disease (CHD) is not established. The few relevant studies did not address operative vaginal delivery. The aim of this study was to assess the impact of fetal CHD on mode of delivery during a trial of labor, and to secondari...

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Autores principales: Zloto, Keren, Hochberg, Alyssa, Tenenbaum-Gavish, Kinneret, Berezowsky, Alexandra, Barbash-Hazan, Shiri, Bardin, Ron, Hadar, Eran, Shmueli, Anat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295291/
https://www.ncbi.nlm.nih.gov/pubmed/35854228
http://dx.doi.org/10.1186/s12884-022-04910-w
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author Zloto, Keren
Hochberg, Alyssa
Tenenbaum-Gavish, Kinneret
Berezowsky, Alexandra
Barbash-Hazan, Shiri
Bardin, Ron
Hadar, Eran
Shmueli, Anat
author_facet Zloto, Keren
Hochberg, Alyssa
Tenenbaum-Gavish, Kinneret
Berezowsky, Alexandra
Barbash-Hazan, Shiri
Bardin, Ron
Hadar, Eran
Shmueli, Anat
author_sort Zloto, Keren
collection PubMed
description BACKGROUND: The optimal mode of delivery in cases of fetal congenital heart disease (CHD) is not established. The few relevant studies did not address operative vaginal delivery. The aim of this study was to assess the impact of fetal CHD on mode of delivery during a trial of labor, and to secondarily describe some obstetric complications. METHODS: The database of a tertiary medical center was searched for women who gave birth to a singleton, liveborn neonate in 2015–2018. Mode of delivery was compared between women carrying a fetus with known CHD and women with a healthy fetus matched 1:5 for maternal age, parity, body mass index, and gestational age. RESULTS: The cohort included 616 women, 105 in the CHD group and 511 in the control group. The rate of operative vaginal delivery was significantly higher in the CHD group (18.09% vs 9.78%, OR 2.03, 95% CI 1.13–3.63, p = 0.01); the difference remained significant after adjustment for nulliparity and gestational age at delivery (aOR 2.58, 95% CI 1.36–4.9, p < 0.01). There was no difference between the CHD and control group in rate of intrapartum cesarean delivery (9.52% vs 10.76%, respectively, OR 0.97, 95% CI 0.47–1.98, p = 0.93). The most common indication for operative vaginal delivery was non-reassuring fetal heart rate (78.94% vs 64%, respectively). Median birth weight percentile was significantly lower in the CHD group (45th vs 53rd percentile, p = 0.04). CONCLUSIONS: Our findings suggest that operative vaginal delivery, performed mostly because of non-reassuring fetal heart rate, is more common in pregnancies complicated by a prenatal diagnosis of CHD than non-anomalous pregnancies.
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spelling pubmed-92952912022-07-20 Fetal congenital heart disease - mode of delivery and obstetrical complications Zloto, Keren Hochberg, Alyssa Tenenbaum-Gavish, Kinneret Berezowsky, Alexandra Barbash-Hazan, Shiri Bardin, Ron Hadar, Eran Shmueli, Anat BMC Pregnancy Childbirth Research BACKGROUND: The optimal mode of delivery in cases of fetal congenital heart disease (CHD) is not established. The few relevant studies did not address operative vaginal delivery. The aim of this study was to assess the impact of fetal CHD on mode of delivery during a trial of labor, and to secondarily describe some obstetric complications. METHODS: The database of a tertiary medical center was searched for women who gave birth to a singleton, liveborn neonate in 2015–2018. Mode of delivery was compared between women carrying a fetus with known CHD and women with a healthy fetus matched 1:5 for maternal age, parity, body mass index, and gestational age. RESULTS: The cohort included 616 women, 105 in the CHD group and 511 in the control group. The rate of operative vaginal delivery was significantly higher in the CHD group (18.09% vs 9.78%, OR 2.03, 95% CI 1.13–3.63, p = 0.01); the difference remained significant after adjustment for nulliparity and gestational age at delivery (aOR 2.58, 95% CI 1.36–4.9, p < 0.01). There was no difference between the CHD and control group in rate of intrapartum cesarean delivery (9.52% vs 10.76%, respectively, OR 0.97, 95% CI 0.47–1.98, p = 0.93). The most common indication for operative vaginal delivery was non-reassuring fetal heart rate (78.94% vs 64%, respectively). Median birth weight percentile was significantly lower in the CHD group (45th vs 53rd percentile, p = 0.04). CONCLUSIONS: Our findings suggest that operative vaginal delivery, performed mostly because of non-reassuring fetal heart rate, is more common in pregnancies complicated by a prenatal diagnosis of CHD than non-anomalous pregnancies. BioMed Central 2022-07-19 /pmc/articles/PMC9295291/ /pubmed/35854228 http://dx.doi.org/10.1186/s12884-022-04910-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Zloto, Keren
Hochberg, Alyssa
Tenenbaum-Gavish, Kinneret
Berezowsky, Alexandra
Barbash-Hazan, Shiri
Bardin, Ron
Hadar, Eran
Shmueli, Anat
Fetal congenital heart disease - mode of delivery and obstetrical complications
title Fetal congenital heart disease - mode of delivery and obstetrical complications
title_full Fetal congenital heart disease - mode of delivery and obstetrical complications
title_fullStr Fetal congenital heart disease - mode of delivery and obstetrical complications
title_full_unstemmed Fetal congenital heart disease - mode of delivery and obstetrical complications
title_short Fetal congenital heart disease - mode of delivery and obstetrical complications
title_sort fetal congenital heart disease - mode of delivery and obstetrical complications
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295291/
https://www.ncbi.nlm.nih.gov/pubmed/35854228
http://dx.doi.org/10.1186/s12884-022-04910-w
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