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Changes in obsessive–compulsive symptoms during inpatient treatment of anorexia nervosa

BACKGROUND: Obsessive–compulsive disorder (OCD) is one of the most prevalent comorbidities in anorexia nervosa (AN). As AN is a severe, life-threatening condition, reducing obsessive–compulsive symptomatology is not the primary objective during treatment of AN and, thus, these symptoms may remain un...

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Autores principales: Meule, Adrian, Voderholzer, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295505/
https://www.ncbi.nlm.nih.gov/pubmed/35851073
http://dx.doi.org/10.1186/s40337-022-00629-3
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author Meule, Adrian
Voderholzer, Ulrich
author_facet Meule, Adrian
Voderholzer, Ulrich
author_sort Meule, Adrian
collection PubMed
description BACKGROUND: Obsessive–compulsive disorder (OCD) is one of the most prevalent comorbidities in anorexia nervosa (AN). As AN is a severe, life-threatening condition, reducing obsessive–compulsive symptomatology is not the primary objective during treatment of AN and, thus, these symptoms may remain unchanged or may even increase in terms of a “symptom shift”. METHODS: In this retrospective analysis, we examined clinical records of 149 adolescents (n = 96, 64%) and adults (n = 53, 36%) with AN (6 males, 4%) who received inpatient treatment and completed the Obsessive–Compulsive Inventory–Revised at admission and discharge. RESULTS: Obsessive–compulsive symptoms decreased from admission to discharge, irrespective of whether patients had comorbid OCD or not. Within-person decreases in obsessive–compulsive symptoms weakly correlated with increases in body weight. CONCLUSIONS: These results indicate that obsessive–compulsive symptoms decrease during inpatient treatment of AN although they are not primarily targeted during treatment. Furthermore, these improvements seem to be associated with general improvements in AN symptomatology, suggesting the absence of a “symptom shift”. Yet, effect sizes were small and obsessive–compulsive symptoms were still clinically elevated in patients with comorbid OCD at discharge, suggesting that these patients need OCD-specific, psychotherapeutic aftercare.
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spelling pubmed-92955052022-07-20 Changes in obsessive–compulsive symptoms during inpatient treatment of anorexia nervosa Meule, Adrian Voderholzer, Ulrich J Eat Disord Research BACKGROUND: Obsessive–compulsive disorder (OCD) is one of the most prevalent comorbidities in anorexia nervosa (AN). As AN is a severe, life-threatening condition, reducing obsessive–compulsive symptomatology is not the primary objective during treatment of AN and, thus, these symptoms may remain unchanged or may even increase in terms of a “symptom shift”. METHODS: In this retrospective analysis, we examined clinical records of 149 adolescents (n = 96, 64%) and adults (n = 53, 36%) with AN (6 males, 4%) who received inpatient treatment and completed the Obsessive–Compulsive Inventory–Revised at admission and discharge. RESULTS: Obsessive–compulsive symptoms decreased from admission to discharge, irrespective of whether patients had comorbid OCD or not. Within-person decreases in obsessive–compulsive symptoms weakly correlated with increases in body weight. CONCLUSIONS: These results indicate that obsessive–compulsive symptoms decrease during inpatient treatment of AN although they are not primarily targeted during treatment. Furthermore, these improvements seem to be associated with general improvements in AN symptomatology, suggesting the absence of a “symptom shift”. Yet, effect sizes were small and obsessive–compulsive symptoms were still clinically elevated in patients with comorbid OCD at discharge, suggesting that these patients need OCD-specific, psychotherapeutic aftercare. BioMed Central 2022-07-18 /pmc/articles/PMC9295505/ /pubmed/35851073 http://dx.doi.org/10.1186/s40337-022-00629-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Meule, Adrian
Voderholzer, Ulrich
Changes in obsessive–compulsive symptoms during inpatient treatment of anorexia nervosa
title Changes in obsessive–compulsive symptoms during inpatient treatment of anorexia nervosa
title_full Changes in obsessive–compulsive symptoms during inpatient treatment of anorexia nervosa
title_fullStr Changes in obsessive–compulsive symptoms during inpatient treatment of anorexia nervosa
title_full_unstemmed Changes in obsessive–compulsive symptoms during inpatient treatment of anorexia nervosa
title_short Changes in obsessive–compulsive symptoms during inpatient treatment of anorexia nervosa
title_sort changes in obsessive–compulsive symptoms during inpatient treatment of anorexia nervosa
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295505/
https://www.ncbi.nlm.nih.gov/pubmed/35851073
http://dx.doi.org/10.1186/s40337-022-00629-3
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