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Phagocytosis converts infiltrated monocytes to microglia-like phenotype in experimental brain ischemia
BACKGROUND: Monocyte-derived macrophages (MDMs) and microglia elicit neural inflammation and clear debris for subsequent tissue repair and remodeling. The role of infiltrating MDMs in the injured brain, however, has been controversial due to overlapping antigen expression with microglia. In this stu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295522/ https://www.ncbi.nlm.nih.gov/pubmed/35850727 http://dx.doi.org/10.1186/s12974-022-02552-5 |