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CD40×HER2 bispecific antibody overcomes the CCL2-induced trastuzumab resistance in HER2-positive gastric cancer
BACKGROUND: There was much hard work to study the trastuzumab resistance in HER2-positive gastric cancer (GC), but the information which would reveal this abstruse mechanism is little. In this study, we aimed to investigate the roles of tumor cell-derived CCL2 on trastuzumab resistance and overcome...
Autores principales: | Sun, Weilin, Wang, Xi, Wang, Daohan, Lu, Li, Lin, Hai, Zhang, Zhaoxiong, Jia, Yangpu, Nie, Xinyang, Liu, Tong, Fu, Weihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295658/ https://www.ncbi.nlm.nih.gov/pubmed/35851310 http://dx.doi.org/10.1136/jitc-2022-005063 |
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