Cargando…
Model-Based Design of a Synthetic Oscillator Based on an Epigenetic Methylation Memory System
[Image: see text] Oscillations are an important component in biological systems; grasping their mechanisms and regulation, however, is difficult. Here, we use the theory of dynamical systems to support the design of oscillatory systems based on epigenetic control elements. Specifically, we use resul...
Autores principales: | Klingel, Viviane, Graf, Dimitri, Weirich, Sara, Jeltsch, Albert, Radde, Nicole E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295699/ https://www.ncbi.nlm.nih.gov/pubmed/35749318 http://dx.doi.org/10.1021/acssynbio.2c00118 |
Ejemplares similares
-
On the accuracy of the epigenetic copy machine: comprehensive specificity analysis of the DNMT1 DNA methyltransferase
por: Adam, Sabrina, et al.
Publicado: (2023) -
Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation
por: Maier, Johannes A. H., et al.
Publicado: (2017) -
Development of an epigenetic tetracycline sensor system based on DNA methylation
por: Ullrich, Timo, et al.
Publicado: (2020) -
Flanking sequences influence the activity of TET1 and TET2 methylcytosine dioxygenases and affect genomic 5hmC patterns
por: Adam, Sabrina, et al.
Publicado: (2022) -
Limited choice of natural amino acids as mimetics restricts design of protein lysine methylation studies
por: Weirich, Sara, et al.
Publicado: (2023)