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CUDC907, a dual phosphoinositide-3 kinase/histone deacetylase inhibitor, promotes apoptosis of NF2 Schwannoma cells

Neurofibromatosis Type 2 (NF2) is a rare tumor disorder caused by pathogenic variants of the merlin tumor suppressor encoded by NF2. Patients develop vestibular schwannomas (VS), peripheral schwannomas, meningiomas, and ependymomas. There are no approved drug therapies for NF2. Previous work identif...

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Detalles Bibliográficos
Autores principales:	Huegel, Julianne, Dinh, Christine T., Martinelli, Maria, Bracho, Olena, Rosario, Rosa, Hardin, Haley, Estivill, Michael, Griswold, Anthony, Gultekin, Sakir, Liu, Xue-Zhong, Fernandez-Valle, Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295707/ https://www.ncbi.nlm.nih.gov/pubmed/35875610 http://dx.doi.org/10.18632/oncotarget.28254

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