Cargando…
Design principles of PI(4,5)P(2) clustering under protein-free conditions: Specific cation effects and calcium-potassium synergy
Phosphatidylinositol 4,5-bisphosphate (PIP(2)) clustering is a key component in cell signaling, yet little is known about the atomic-level features of this phenomenon. Network-theoretic analysis of multimicrosecond atomistic simulations of PIP(2) containing asymmetric bilayers under protein-free con...
Autores principales: | Han, Kyungreem, Kim, Soon Ho, Venable, Richard M., Pastor, Richard W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295730/ https://www.ncbi.nlm.nih.gov/pubmed/35605121 http://dx.doi.org/10.1073/pnas.2202647119 |
Ejemplares similares
-
PLD2–PI(4,5)P2 interactions in fluid phase membranes: Structural modeling and molecular dynamics simulations
por: Han, Kyungreem, et al.
Publicado: (2020) -
"Caged calcium" in Aplysia pacemaker neurons. Characterization of calcium-activated potassium and nonspecific cation currents
Publicado: (1989) -
Regulation of voltage-gated potassium channels by PI(4,5)P(2)
por: Kruse, Martin, et al.
Publicado: (2012) -
First-principles data set of 45,892 isolated and cation-coordinated conformers of 20 proteinogenic amino acids
por: Ropo, Matti, et al.
Publicado: (2016) -
Distinct subunit contributions to the activation of M-type potassium channels by PI(4,5)P(2)
por: Telezhkin, Vsevolod, et al.
Publicado: (2012)