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Design principles of PI(4,5)P(2) clustering under protein-free conditions: Specific cation effects and calcium-potassium synergy

Phosphatidylinositol 4,5-bisphosphate (PIP(2)) clustering is a key component in cell signaling, yet little is known about the atomic-level features of this phenomenon. Network-theoretic analysis of multimicrosecond atomistic simulations of PIP(2) containing asymmetric bilayers under protein-free con...

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Detalles Bibliográficos
Autores principales: Han, Kyungreem, Kim, Soon Ho, Venable, Richard M., Pastor, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295730/
https://www.ncbi.nlm.nih.gov/pubmed/35605121
http://dx.doi.org/10.1073/pnas.2202647119

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