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Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation

Polycomb-group proteins play critical roles in gene silencing through the deposition of histone H3 lysine 27 trimethylation (H3K27me3) and chromatin compaction. This process is essential for embryonic stem cell (ESC) pluripotency, differentiation, and development. Polycomb repressive complex 2 (PRC2...

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Detalles Bibliográficos
Autores principales:	Kraft, Katerina, Yost, Kathryn E., Murphy, Sedona E., Magg, Andreas, Long, Yicheng, Corces, M. Ryan, Granja, Jeffrey M., Wittler, Lars, Mundlos, Stefan, Cech, Thomas R., Boettiger, Alistair N., Chang, Howard Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295753/ https://www.ncbi.nlm.nih.gov/pubmed/35617427 http://dx.doi.org/10.1073/pnas.2201883119

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