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Orc6 is a component of the replication fork and enables efficient mismatch repair

In eukaryotes, the origin recognition complex (ORC) is required for the initiation of DNA replication. The smallest subunit of ORC, Orc6, is essential for prereplication complex (pre-RC) assembly and cell viability in yeast and for cytokinesis in metazoans. However, unlike other ORC components, the...

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Detalles Bibliográficos
Autores principales: Lin, Yo-Chuen, Liu, Dazhen, Chakraborty, Arindam, Kadyrova, Lyudmila Y., Song, You Jin, Hao, Qinyu, Mitra, Jaba, Hsu, Rosaline Y. C., Arif, Mariam K., Adusumilli, Sneha, Liao, Ting-Wei, Ha, Taekjip, Kadyrov, Farid A., Prasanth, Kannanganattu V., Prasanth, Supriya G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295755/
https://www.ncbi.nlm.nih.gov/pubmed/35622890
http://dx.doi.org/10.1073/pnas.2121406119