Zinc finger protein 280C contributes to colorectal tumorigenesis by maintaining epigenetic repression at H3K27me3-marked loci

Dysregulated epigenetic and transcriptional programming due to abnormalities of transcription factors (TFs) contributes to and sustains the oncogenicity of cancer cells. Here, we unveiled the role of zinc finger protein 280C (ZNF280C), a known DNA damage response protein, as a tumorigenic TF in colo...

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Detalles Bibliográficos
Autores principales: Ying, Ying, Wang, Maolin, Chen, Yongheng, Li, Meiqi, Ma, Canjie, Zhang, Junbao, Huang, Xiaoyan, Jia, Min, Zeng, Junhui, Wang, Yejun, Li, Lili, Wang, Xiaomei, Tao, Qian, Shu, Xing-sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295756/
https://www.ncbi.nlm.nih.gov/pubmed/35605119
http://dx.doi.org/10.1073/pnas.2120633119

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