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Variants of the guanine riboswitch class exhibit altered ligand specificities for xanthine, guanine, or 2′-deoxyguanosine

The aptamer portions of previously reported riboswitch classes that sense guanine, adenine, or 2′-deoxyguanosine are formed by a highly similar three-stem junction with distinct nucleotide sequences in the regions joining the stems. The nucleotides in these joining regions form the major features of...

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Detalles Bibliográficos
Autores principales: Hamal Dhakal, Siddhartha, Panchapakesan, Shanker S. S., Slattery, Paul, Roth, Adam, Breaker, Ronald R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295807/
https://www.ncbi.nlm.nih.gov/pubmed/35622895
http://dx.doi.org/10.1073/pnas.2120246119