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Savior Siblings Might Rescue Fetal Lethality But Not Adult Lymphoma in Irf2bp2-Null Mice

Interferon regulatory factor 2 binding protein 2 (Irf2bp2), a co-repressor of Irf2, is required for fetal hepatic erythropoiesis through the expansion of erythromyeloid progenitors. Mice with germline ablation of the entire Irf2bp2 transcript produced no viable Irf2bp2-null pups in first litters. In...

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Detalles Bibliográficos
Autores principales: Vilmundarson, Ragnar O., Heydarikhorneh, Niloufar, Duong, An, Ho, Tiffany, Keyhanian, Kianoosh, Soheili, Fariborz, Chen, Hsiao-Huei, Stewart, Alexandre F. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295810/
https://www.ncbi.nlm.nih.gov/pubmed/35865523
http://dx.doi.org/10.3389/fimmu.2022.868053