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Human Hepatic CD56(bright) NK Cells Display a Tissue-Resident Transcriptional Profile and Enhanced Ability to Kill Allogenic CD8(+) T Cells
Liver-resident CD56(bright)CD16(-) natural killer (NK) cells are enriched in the human liver and are phenotypically distinct from their blood counterparts. Although these cells are capable of rapid cytotoxic effector activity, their functional role remains unclear. We hypothesise that they may contr...
Autores principales: | Jameson, Gráinne, Harmon, Cathal, Santiago, Rhyla Mae, Houlihan, Diarmaid D., Gallagher, Tom K., Lynch, Lydia, Robinson, Mark W., O’Farrelly, Cliona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295839/ https://www.ncbi.nlm.nih.gov/pubmed/35865550 http://dx.doi.org/10.3389/fimmu.2022.921212 |
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