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Human Hepatic CD56(bright) NK Cells Display a Tissue-Resident Transcriptional Profile and Enhanced Ability to Kill Allogenic CD8(+) T Cells

Liver-resident CD56(bright)CD16(-) natural killer (NK) cells are enriched in the human liver and are phenotypically distinct from their blood counterparts. Although these cells are capable of rapid cytotoxic effector activity, their functional role remains unclear. We hypothesise that they may contr...

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Detalles Bibliográficos
Autores principales: Jameson, Gráinne, Harmon, Cathal, Santiago, Rhyla Mae, Houlihan, Diarmaid D., Gallagher, Tom K., Lynch, Lydia, Robinson, Mark W., O’Farrelly, Cliona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295839/
https://www.ncbi.nlm.nih.gov/pubmed/35865550
http://dx.doi.org/10.3389/fimmu.2022.921212

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