A COVID-19 Patient Discharged According to Strict Discharge Standards: Viral Negativity in Both Nasopharynx and Feces

Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) currently has spread all over the world. However, the dynamic characteristics of SARS-CoV-2 infections have not previously been described in detail. Here, we report a cured patient in West China Hospital, and describe the dynamic detection...

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Autores principales: Chen, Enqiang, Wang, Lichun, Tang, Guangming, Wang, Menglan, Tao, Yachao, Feng, Ping, Tang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Short Report & Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295935/
https://www.ncbi.nlm.nih.gov/pubmed/37520108
http://dx.doi.org/10.1097/ID9.0000000000000040
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author Chen, Enqiang
Wang, Lichun
Tang, Guangming
Wang, Menglan
Tao, Yachao
Feng, Ping
Tang, Hong
author_facet Chen, Enqiang
Wang, Lichun
Tang, Guangming
Wang, Menglan
Tao, Yachao
Feng, Ping
Tang, Hong
author_sort Chen, Enqiang
collection PubMed
description Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) currently has spread all over the world. However, the dynamic characteristics of SARS-CoV-2 infections have not previously been described in detail. Here, we report a cured patient in West China Hospital, and describe the dynamic detection of SARS-CoV-2-RNA in different specimens and viral specific IgM and IgG antibodies in blood. The findings suggest that the fecal SARS-CoV-2-RNA negativity may be considered as a new standard for de isolation. Serum IgM and IgG antibodies detection were helpful for early diagnosis of SARS-CoV-2 infection and judgment of patients in recovery stage, respectively.
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spelling pubmed-92959352022-08-03 A COVID-19 Patient Discharged According to Strict Discharge Standards: Viral Negativity in Both Nasopharynx and Feces Chen, Enqiang Wang, Lichun Tang, Guangming Wang, Menglan Tao, Yachao Feng, Ping Tang, Hong Infectious Diseases & Immunity Short Report & Case Report Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) currently has spread all over the world. However, the dynamic characteristics of SARS-CoV-2 infections have not previously been described in detail. Here, we report a cured patient in West China Hospital, and describe the dynamic detection of SARS-CoV-2-RNA in different specimens and viral specific IgM and IgG antibodies in blood. The findings suggest that the fecal SARS-CoV-2-RNA negativity may be considered as a new standard for de isolation. Serum IgM and IgG antibodies detection were helpful for early diagnosis of SARS-CoV-2 infection and judgment of patients in recovery stage, respectively. Lippincott Williams & Wilkins 2022-01-05 /pmc/articles/PMC9295935/ /pubmed/37520108 http://dx.doi.org/10.1097/ID9.0000000000000040 Text en Copyright © 2022 The Chinese Medical Association, published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.
spellingShingle Short Report & Case Report
Chen, Enqiang
Wang, Lichun
Tang, Guangming
Wang, Menglan
Tao, Yachao
Feng, Ping
Tang, Hong
A COVID-19 Patient Discharged According to Strict Discharge Standards: Viral Negativity in Both Nasopharynx and Feces
title A COVID-19 Patient Discharged According to Strict Discharge Standards: Viral Negativity in Both Nasopharynx and Feces
title_full A COVID-19 Patient Discharged According to Strict Discharge Standards: Viral Negativity in Both Nasopharynx and Feces
title_fullStr A COVID-19 Patient Discharged According to Strict Discharge Standards: Viral Negativity in Both Nasopharynx and Feces
title_full_unstemmed A COVID-19 Patient Discharged According to Strict Discharge Standards: Viral Negativity in Both Nasopharynx and Feces
title_short A COVID-19 Patient Discharged According to Strict Discharge Standards: Viral Negativity in Both Nasopharynx and Feces
title_sort covid-19 patient discharged according to strict discharge standards: viral negativity in both nasopharynx and feces
topic Short Report & Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295935/
https://www.ncbi.nlm.nih.gov/pubmed/37520108
http://dx.doi.org/10.1097/ID9.0000000000000040
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