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Detection of BPDE-DNA adducts in human umbilical cord blood by LC-MS/MS analysis

Benzo [a]pyrene (BaP) is a model compound for the study of polycyclic aromatic hydrocarbon (PAH) carcinogenesis. Upon metabolism, BaP is metabolized to the ultimate metabolite, BaP trans-7,8-diol-anti-9,10-epoxide (BPDE), that reacts with cellular DNA to form BPDE-dG adducts responsible for BaP-indu...

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Detalles Bibliográficos
Autores principales:	Guo, Ling, Jiang, Xiao, Tian, Hao-Yuan, Yao, Shang-Jin, Li, Bo-Ya, Zhang, Rong-Jie, Zhang, Shu-Sheng, Sun, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taiwan Food and Drug Administration 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296209/ https://www.ncbi.nlm.nih.gov/pubmed/30987723 http://dx.doi.org/10.1016/j.jfda.2019.03.001

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