Dextran Mass Ratio Controls Particle Drying Dynamics in a Thermally Stable Dry Powder Vaccine for Pulmonary Delivery

PURPOSE: Thermally stable, spray dried vaccines targeting respiratory diseases are promising candidates for pulmonary delivery, requiring careful excipient formulation to effectively encapsulate and protect labile biologics. This study investigates the impact of dextran mass ratio and molecular weig...

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Detalles Bibliográficos
Autores principales: Manser, Myla, Morgan, Blair A., Feng, Xueya, Rhem, Rod G., Dolovich, Myrna B., Xing, Zhou, Cranston, Emily D., Thompson, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296218/
https://www.ncbi.nlm.nih.gov/pubmed/35854077
http://dx.doi.org/10.1007/s11095-022-03341-8

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