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The mechanism of replication stalling and recovery within repetitive DNA

Accurate chromosomal DNA replication is essential to maintain genomic stability. Genetic evidence suggests that certain repetitive sequences impair replication, yet the underlying mechanism is poorly defined. Replication could be directly inhibited by the DNA template or indirectly, for example by D...

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Detalles Bibliográficos
Autores principales: Casas-Delucchi, Corella S., Daza-Martin, Manuel, Williams, Sophie L., Coster, Gideon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296464/
https://www.ncbi.nlm.nih.gov/pubmed/35853874
http://dx.doi.org/10.1038/s41467-022-31657-x