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Allogeneic MHC-matched T-cell receptor α/β-depleted bone marrow transplants in SHIV-infected, ART-suppressed Mauritian cynomolgus macaques

Allogeneic hematopoietic stem cell transplants (allo-HSCTs) dramatically reduce HIV reservoirs in antiretroviral therapy (ART) suppressed individuals. However, the mechanism(s) responsible for these post-transplant viral reservoir declines are not fully understood. Therefore, we modeled allo-HSCT in...

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Detalles Bibliográficos
Autores principales: Weinfurter, Jason T., D’Souza, Saritha S., Matschke, Lea M., Bennett, Sarah, Kelnhofer-Millevolte, Laurel E., Suknuntha, Kran, Kumar, Akhilesh, Coonen, Jennifer, Capitini, Christian M., Hematti, Peiman, Golos, Thaddeus G., Slukvin, Igor I., Reynolds, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296477/
https://www.ncbi.nlm.nih.gov/pubmed/35853970
http://dx.doi.org/10.1038/s41598-022-16306-z

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