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Multifocal organoids reveal clonal associations between synchronous intestinal tumors with pervasive heterogeneous drug responses

Multifocal colorectal cancer (CRC) comprises both clonally independent primary tumors caused by inherited predisposition and clonally related tumors mainly due to intraluminal spreading along an intact basement membrane. The distinction between these multifocal CRCs is essential because therapeutic...

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Detalles Bibliográficos
Autores principales: Jeong, Nahyun, Kim, Soon-Chan, Park, Ji Won, Park, Seul Gi, Nam, Ki-Hoan, Lee, Ja Oh, Shin, Young-Kyoung, Bae, Jeong Mo, Jeong, Seung-Yong, Kim, Min Jung, Ku, Ja-Lok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296490/
https://www.ncbi.nlm.nih.gov/pubmed/35853873
http://dx.doi.org/10.1038/s41525-022-00313-0

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