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Multifocal organoids reveal clonal associations between synchronous intestinal tumors with pervasive heterogeneous drug responses
Multifocal colorectal cancer (CRC) comprises both clonally independent primary tumors caused by inherited predisposition and clonally related tumors mainly due to intraluminal spreading along an intact basement membrane. The distinction between these multifocal CRCs is essential because therapeutic...
Autores principales: | Jeong, Nahyun, Kim, Soon-Chan, Park, Ji Won, Park, Seul Gi, Nam, Ki-Hoan, Lee, Ja Oh, Shin, Young-Kyoung, Bae, Jeong Mo, Jeong, Seung-Yong, Kim, Min Jung, Ku, Ja-Lok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296490/ https://www.ncbi.nlm.nih.gov/pubmed/35853873 http://dx.doi.org/10.1038/s41525-022-00313-0 |
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