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Direct cleavage of caspase-8 by herpes simplex virus 1 tegument protein US11

The HSV-1 tegument protein Us11 counteracts the antiviral defense mechanisms by precluding the host protein shutoff. Previous works demonstrated that Us11 prevents heat-and staurosporine-induced apoptosis and inhibits autophagy. Therefore, in the present study, we investigated the hypothesis that HS...

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Detalles Bibliográficos
Autores principales: Musarra-Pizzo, Maria, Pennisi, Rosamaria, Lombardo, Daniele, Velletri, Tania, Sciortino, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296525/
https://www.ncbi.nlm.nih.gov/pubmed/35853963
http://dx.doi.org/10.1038/s41598-022-15942-9