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Effects of intermittent hypoxia with thrombin in an in vitro model of human brain endothelial cells and their impact on PAR-1/PAR-3 cleavage

Patients with obstructive sleep apnea/hypopnea (OSA) are at high risk of cerebrovascular diseases leading to cognitive impairment. The oxidative stress generated by intermittent hypoxia (IH) could lead to an increase in blood–brain barrier (BBB) permeability, an essential interface for the protectio...

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Detalles Bibliográficos
Autores principales:	Zolotoff, Cindy, Puech, Clémentine, Roche, Frédéric, Perek, Nathalie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296553/ https://www.ncbi.nlm.nih.gov/pubmed/35853902 http://dx.doi.org/10.1038/s41598-022-15592-x

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