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HDAC4 promotes the growth and metastasis of gastric cancer via autophagic degradation of MEKK3

BACKGROUND: Histone deacetylases (HDACs) have been shown to be involved in tumorigenesis, but their precise role and molecular mechanisms in gastric cancer (GC) have not yet been fully elucidated. METHODS: Bioinformatics screening analysis, qRT-PCR, and immunohistochemistry (IHC) were used to identi...

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Detalles Bibliográficos
Autores principales:	Zang, Wei-Jie, Hu, Yi-Lin, Qian, Chen-Yu, Feng, Ying, Liu, Jia-Zhou, Yang, Jun-Ling, Huang, Hua, Zhu, Yi-Zhun, Xue, Wan-Jiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296555/ https://www.ncbi.nlm.nih.gov/pubmed/35637410 http://dx.doi.org/10.1038/s41416-022-01805-7

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