Un-biased housekeeping gene panel selection for high-validity gene expression analysis

Differential gene expression normalised to a single housekeeping (HK) is used to identify disease mechanisms and therapeutic targets. HK gene selection is often arbitrary, potentially introducing systematic error and discordant results. Here we examine these risks in a disease model of brain hypoxia...

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Detalles Bibliográficos
Autores principales: Casas, Ana I., Hassan, Ahmed A., Manz, Quirin, Wiwie, Christian, Kleikers, Pamela, Egea, Javier, López, Manuela G., List, Markus, Baumbach, Jan, Schmidt, Harald H. H. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296577/
https://www.ncbi.nlm.nih.gov/pubmed/35853974
http://dx.doi.org/10.1038/s41598-022-15989-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296577/
https://www.ncbi.nlm.nih.gov/pubmed/35853974
http://dx.doi.org/10.1038/s41598-022-15989-8

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