Genome-wide CRISPR screen for HSV-1 host factors reveals PAPSS1 contributes to heparan sulfate synthesis

Herpes simplex virus type 1 (HSV-1) is a ubiquitous pathogen that causes various diseases in humans, ranging from common mucocutaneous lesions to severe life-threatening encephalitis. However, our understanding of the interaction between HSV-1 and human host factors remains incomplete. Here, to iden...

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Detalles Bibliográficos
Autores principales: Suzuki, Takeshi, Sato, Yoshitaka, Okuno, Yusuke, Goshima, Fumi, Mikami, Tadahisa, Umeda, Miki, Murata, Takayuki, Watanabe, Takahiro, Watashi, Koichi, Wakita, Takaji, Kitagawa, Hiroshi, Kimura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296583/
https://www.ncbi.nlm.nih.gov/pubmed/35854076
http://dx.doi.org/10.1038/s42003-022-03581-9

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