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Protective effects of rituximab on puromycin-induced apoptosis, loss of adhesion and cytoskeletal alterations in human podocytes

Podocytes are highly specialized cells playing a key role in the filtration function of the kidney. A damaged podocyte ultrastructure is associated with a reorganization of the actin cytoskeleton and accompanied with a loss of adhesion to the glomerular basement membrane leading to proteinuria in ma...

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Detalles Bibliográficos
Autores principales: Jeruschke, Stefanie, Alex, Dana, Hoyer, Peter Friedrich, Weber, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296604/
https://www.ncbi.nlm.nih.gov/pubmed/35853959
http://dx.doi.org/10.1038/s41598-022-16333-w

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