Anti-cancer therapy is associated with long-term epigenomic changes in childhood cancer survivors

BACKGROUND: Childhood cancer survivors (CCS) exhibit significantly increased chronic diseases and premature death. Abnormalities in DNA methylation are associated with development of chronic diseases and reduced life expectancy. We investigated the hypothesis that anti-cancer treatments are associat...

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Detalles Bibliográficos
Autores principales: Robinson, Natassia, Casement, John, Gunter, Marc J., Huybrechts, Inge, Agudo, Antonio, Barranco, Miguel Rodríguez, Eichelmann, Fabian, Johnson, Theron, Kaaks, Rudolf, Pala, Valeria, Panico, Salvatore, Sandanger, Torkjel M., Schultze, Matthias B., Travis, Ruth C., Tumino, Rosario, Vineis, Paolo, Weiderpass, Elisabete, Skinner, Roderick, Sharp, Linda, McKay, Jill A, Strathdee, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296636/
https://www.ncbi.nlm.nih.gov/pubmed/35354948
http://dx.doi.org/10.1038/s41416-022-01792-9

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