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Conformational landscape of the yeast SAGA complex as revealed by cryo-EM

Spt-Ada-Gcn5-Acetyltransferase (SAGA) is a conserved multi-subunit complex that activates RNA polymerase II-mediated transcription by acetylating and deubiquitinating nucleosomal histones and by recruiting TATA box binding protein (TBP) to DNA. The prototypical yeast Saccharomyces cerevisiae SAGA co...

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Detalles Bibliográficos
Autores principales: Vasyliuk, Diana, Felt, Joeseph, Zhong, Ellen D., Berger, Bonnie, Davis, Joseph H., Yip, Calvin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296673/
https://www.ncbi.nlm.nih.gov/pubmed/35853968
http://dx.doi.org/10.1038/s41598-022-16391-0