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Systematic Review of Safety and Efficacy of IL-1-Targeted Biologics in Treating Immune-Mediated Disorders

BACKGROUND: The cytokine interleukin (IL)-1 plays a pivotal role in immune-mediated disorders, particularly in autoinflammatory diseases. Targeting this cytokine proved to be efficacious in treating numerous IL-1-mediated pathologies. Currently, three IL-1 blockers are approved, namely anakinra, can...

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Detalles Bibliográficos
Autores principales: Arnold, Dennis D., Yalamanoglu, Ayla, Boyman, Onur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296857/
https://www.ncbi.nlm.nih.gov/pubmed/35874710
http://dx.doi.org/10.3389/fimmu.2022.888392