Dual Antigen T Cell Engagers Targeting CA9 as an Effective Immunotherapeutic Modality for Targeting CA9 in Solid Tumors

Glioblastomas (GBM), the most common malignant primary adult brain tumors, are uniformly lethal and are in need of improved therapeutic modalities. GBM contain extensive regions of hypoxia and are enriched in therapy resistant brain tumor-initiating cells (BTICs). Carbonic anhydrase 9 (CA9) is a hyp...

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Detalles Bibliográficos
Autores principales: Tatari, Nazanin, Zhang, Xiaoyu, Chafe, Shawn C., McKenna, Dillon, Lawson, Keith A., Subapanditha, Minomi, Shaikh, Muhammad Vaseem, Seyfrid, Mathieu, Savage, Neil, Venugopal, Chitra, Moffat, Jason, Singh, Sheila K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296860/
https://www.ncbi.nlm.nih.gov/pubmed/35874663
http://dx.doi.org/10.3389/fimmu.2022.905768

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