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MET-PREVENT: metformin to improve physical performance in older people with sarcopenia and physical prefrailty/frailty – protocol for a double-blind, randomised controlled proof-of-concept trial

INTRODUCTION: Skeletal muscle dysfunction is central to both sarcopenia and physical frailty, which are associated with a wide range of adverse outcomes including falls and fractures, longer hospital stays, dependency and the need for care. Resistance training may prevent and treat sarcopenia and ph...

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Detalles Bibliográficos
Autores principales: Rennie, Katherine J, Witham, Miles, Bradley, Penny, Clegg, Andrew, Connolly, Stephen, Hancock, Helen C, Hiu, Shaun, Marsay, Leanne, McDonald, Claire, Robertson, Laura, Simms, Laura, Steel, Alison J, Steves, Claire J, Storey, Bryony, Wason, James, Wilson, Nina, von Zglinicki, Thomas, Sayer, Avan A P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297211/
https://www.ncbi.nlm.nih.gov/pubmed/35851031
http://dx.doi.org/10.1136/bmjopen-2022-061823