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MET-PREVENT: metformin to improve physical performance in older people with sarcopenia and physical prefrailty/frailty – protocol for a double-blind, randomised controlled proof-of-concept trial
INTRODUCTION: Skeletal muscle dysfunction is central to both sarcopenia and physical frailty, which are associated with a wide range of adverse outcomes including falls and fractures, longer hospital stays, dependency and the need for care. Resistance training may prevent and treat sarcopenia and ph...
Autores principales: | Rennie, Katherine J, Witham, Miles, Bradley, Penny, Clegg, Andrew, Connolly, Stephen, Hancock, Helen C, Hiu, Shaun, Marsay, Leanne, McDonald, Claire, Robertson, Laura, Simms, Laura, Steel, Alison J, Steves, Claire J, Storey, Bryony, Wason, James, Wilson, Nina, von Zglinicki, Thomas, Sayer, Avan A P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297211/ https://www.ncbi.nlm.nih.gov/pubmed/35851031 http://dx.doi.org/10.1136/bmjopen-2022-061823 |
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