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Luminescent PLGA Nanoparticles for Delivery of Darunavir to the Brain and Inhibition of Matrix Metalloproteinase-9, a Relevant Therapeutic Target of HIV-Associated Neurological Disorders

[Image: see text] Human immunodeficiency virus (HIV) can independently replicate in the central nervous system (CNS) causing neurocognitive impairment even in subjects with suppressed plasma viral load. The antiretroviral drug darunavir (DRV) has been approved for therapy of HIV-infected patients, b...

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Detalles Bibliográficos
Autores principales:	Latronico, Tiziana, Rizzi, Federica, Panniello, Annamaria, Laquintana, Valentino, Arduino, Ilaria, Denora, Nunzio, Fanizza, Elisabetta, Milella, Serafina, Mastroianni, Claudio M., Striccoli, Marinella, Curri, Maria Lucia, Liuzzi, Grazia M., Depalo, Nicoletta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297288/ https://www.ncbi.nlm.nih.gov/pubmed/34726377 http://dx.doi.org/10.1021/acschemneuro.1c00436

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