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Raised D-dimer among Admitted COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study

INTRODUCTION: Patients with COVID-19 are characterised by abnormal levels of inflammatory biomarkers. Elevated D-dimer in COVID-19 patients is associated with increased mortality. This study aimed to find out the prevalence of raised D-dimer among COVID-19 patients in a tertiary care centre. METHODS...

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Autores principales: Karki, Dipesh, Gurung, Roshani, Nepali, Prasanna, Kaphle, Hari Prasad, Subedi, Bhabuk, Adhikari, Sundar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297361/
https://www.ncbi.nlm.nih.gov/pubmed/36705193
http://dx.doi.org/10.31729/jnma.7579
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author Karki, Dipesh
Gurung, Roshani
Nepali, Prasanna
Kaphle, Hari Prasad
Subedi, Bhabuk
Adhikari, Sundar
author_facet Karki, Dipesh
Gurung, Roshani
Nepali, Prasanna
Kaphle, Hari Prasad
Subedi, Bhabuk
Adhikari, Sundar
author_sort Karki, Dipesh
collection PubMed
description INTRODUCTION: Patients with COVID-19 are characterised by abnormal levels of inflammatory biomarkers. Elevated D-dimer in COVID-19 patients is associated with increased mortality. This study aimed to find out the prevalence of raised D-dimer among COVID-19 patients in a tertiary care centre. METHODS: This descriptive cross-sectional study was conducted in COVID-19 unit of a tertiary care centre from 23 January 2021 to 19 June 2021. The ethical approval was taken from the Institutional Review Committee (Reference number: 077/078/159). D-dimer values and demographic data of the hospital-admitted COVID-19 patients were recorded. Convenience sampling technique was used. Point estimate and 95% Confidence Interval were calculated. RESULTS: Out of 180 patients with COVID-19 admitted in the hospital, the D-dimer levels were raised in 85 (47.22%) (39.93-54.51, 95% Confidence Interval) patients. CONCLUSIONS: The prevalence of raised D-dimer among admitted COVID-19 patients was found to be lower when compared to other studies conducted in similar settings.
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spelling pubmed-92973612022-07-20 Raised D-dimer among Admitted COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study Karki, Dipesh Gurung, Roshani Nepali, Prasanna Kaphle, Hari Prasad Subedi, Bhabuk Adhikari, Sundar JNMA J Nepal Med Assoc Original Article INTRODUCTION: Patients with COVID-19 are characterised by abnormal levels of inflammatory biomarkers. Elevated D-dimer in COVID-19 patients is associated with increased mortality. This study aimed to find out the prevalence of raised D-dimer among COVID-19 patients in a tertiary care centre. METHODS: This descriptive cross-sectional study was conducted in COVID-19 unit of a tertiary care centre from 23 January 2021 to 19 June 2021. The ethical approval was taken from the Institutional Review Committee (Reference number: 077/078/159). D-dimer values and demographic data of the hospital-admitted COVID-19 patients were recorded. Convenience sampling technique was used. Point estimate and 95% Confidence Interval were calculated. RESULTS: Out of 180 patients with COVID-19 admitted in the hospital, the D-dimer levels were raised in 85 (47.22%) (39.93-54.51, 95% Confidence Interval) patients. CONCLUSIONS: The prevalence of raised D-dimer among admitted COVID-19 patients was found to be lower when compared to other studies conducted in similar settings. Journal of the Nepal Medical Association 2022-07 2022-07-31 /pmc/articles/PMC9297361/ /pubmed/36705193 http://dx.doi.org/10.31729/jnma.7579 Text en © The Author(s) 2018. https://creativecommons.org/licenses/by/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Karki, Dipesh
Gurung, Roshani
Nepali, Prasanna
Kaphle, Hari Prasad
Subedi, Bhabuk
Adhikari, Sundar
Raised D-dimer among Admitted COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title Raised D-dimer among Admitted COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_full Raised D-dimer among Admitted COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_fullStr Raised D-dimer among Admitted COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_full_unstemmed Raised D-dimer among Admitted COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_short Raised D-dimer among Admitted COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_sort raised d-dimer among admitted covid-19 patients in a tertiary care centre: a descriptive cross-sectional study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297361/
https://www.ncbi.nlm.nih.gov/pubmed/36705193
http://dx.doi.org/10.31729/jnma.7579
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