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Effect of standardized root extract of ashwagandha (Withania somnifera) on well‐being and sexual performance in adult males: A randomized controlled trial

BACKGROUND AND AIM: In Ayurveda, ashwagandha is a popular plant for promoting youthful energy, longevity, and overall well‐being. It is also an excellent aphrodisiac herb that aids in the improvement and maintenance of normal sexual health. The present study aims to evaluate the effect of ashwagandh...

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Autores principales: Chauhan, Sanjaya, Srivastava, Manoj K., Pathak, Anklesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297375/
https://www.ncbi.nlm.nih.gov/pubmed/35873404
http://dx.doi.org/10.1002/hsr2.741
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author Chauhan, Sanjaya
Srivastava, Manoj K.
Pathak, Anklesh K.
author_facet Chauhan, Sanjaya
Srivastava, Manoj K.
Pathak, Anklesh K.
author_sort Chauhan, Sanjaya
collection PubMed
description BACKGROUND AND AIM: In Ayurveda, ashwagandha is a popular plant for promoting youthful energy, longevity, and overall well‐being. It is also an excellent aphrodisiac herb that aids in the improvement and maintenance of normal sexual health. The present study aims to evaluate the effect of ashwagandha root extract on improving sexual health in adult males. METHODS: In this 8‐week randomized, double‐blind, placebo‐controlled study, we investigated the aphrodisiac property of an ashwagandha root extract in adult males. Fifty participants with lower sexual desire were randomly allocated to take 300 mg of ashwagandha root extract or placebo capsules twice daily. Outcomes were measured using the derogatis interview for sexual functioning‐male (DISF‐M) questionnaire, serum testosterone, serum prolactin, and short‐form survey—36 quality of life questionnaire before and after the intervention. RESULTS: Compared to placebo, ashwagandha root extract supplementation was associated with a statistically significant increase in the total DISF‐M scores (mean difference −9.8; 95% confidence interval, −10.73 to −8.87; p < 0.0001; t‐test). It was also associated with a statistically significant increase in serum testosterone levels (−66.52; −80.70 to −52.34; p < 0.0001; t‐test). However, the prolactin level did not change after intervention in both the ashwagandha and placebo groups (−1.06; −2.78 to 0.66; p > 0.05). CONCLUSION: These findings suggest that ashwagandha demonstrated a significant subjective perception of sexual well‐being and assisted in increasing serum testosterone levels in the participants.
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spelling pubmed-92973752022-07-22 Effect of standardized root extract of ashwagandha (Withania somnifera) on well‐being and sexual performance in adult males: A randomized controlled trial Chauhan, Sanjaya Srivastava, Manoj K. Pathak, Anklesh K. Health Sci Rep Original Research BACKGROUND AND AIM: In Ayurveda, ashwagandha is a popular plant for promoting youthful energy, longevity, and overall well‐being. It is also an excellent aphrodisiac herb that aids in the improvement and maintenance of normal sexual health. The present study aims to evaluate the effect of ashwagandha root extract on improving sexual health in adult males. METHODS: In this 8‐week randomized, double‐blind, placebo‐controlled study, we investigated the aphrodisiac property of an ashwagandha root extract in adult males. Fifty participants with lower sexual desire were randomly allocated to take 300 mg of ashwagandha root extract or placebo capsules twice daily. Outcomes were measured using the derogatis interview for sexual functioning‐male (DISF‐M) questionnaire, serum testosterone, serum prolactin, and short‐form survey—36 quality of life questionnaire before and after the intervention. RESULTS: Compared to placebo, ashwagandha root extract supplementation was associated with a statistically significant increase in the total DISF‐M scores (mean difference −9.8; 95% confidence interval, −10.73 to −8.87; p < 0.0001; t‐test). It was also associated with a statistically significant increase in serum testosterone levels (−66.52; −80.70 to −52.34; p < 0.0001; t‐test). However, the prolactin level did not change after intervention in both the ashwagandha and placebo groups (−1.06; −2.78 to 0.66; p > 0.05). CONCLUSION: These findings suggest that ashwagandha demonstrated a significant subjective perception of sexual well‐being and assisted in increasing serum testosterone levels in the participants. John Wiley and Sons Inc. 2022-07-20 /pmc/articles/PMC9297375/ /pubmed/35873404 http://dx.doi.org/10.1002/hsr2.741 Text en © 2022 The Authors. Health Science Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Research
Chauhan, Sanjaya
Srivastava, Manoj K.
Pathak, Anklesh K.
Effect of standardized root extract of ashwagandha (Withania somnifera) on well‐being and sexual performance in adult males: A randomized controlled trial
title Effect of standardized root extract of ashwagandha (Withania somnifera) on well‐being and sexual performance in adult males: A randomized controlled trial
title_full Effect of standardized root extract of ashwagandha (Withania somnifera) on well‐being and sexual performance in adult males: A randomized controlled trial
title_fullStr Effect of standardized root extract of ashwagandha (Withania somnifera) on well‐being and sexual performance in adult males: A randomized controlled trial
title_full_unstemmed Effect of standardized root extract of ashwagandha (Withania somnifera) on well‐being and sexual performance in adult males: A randomized controlled trial
title_short Effect of standardized root extract of ashwagandha (Withania somnifera) on well‐being and sexual performance in adult males: A randomized controlled trial
title_sort effect of standardized root extract of ashwagandha (withania somnifera) on well‐being and sexual performance in adult males: a randomized controlled trial
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297375/
https://www.ncbi.nlm.nih.gov/pubmed/35873404
http://dx.doi.org/10.1002/hsr2.741
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