Asymmetric synthesis of aryl/vinyl alkyl carbinol esters via Ni-catalyzed reductive arylation/vinylation of 1-chloro-1-alkanol esters

We report herein an asymmetric Ni-catalyzed cross-electrophile coupling approach to prepare enantioenriched aryl/vinyl alkyl carbinol esters through arylation/vinylation of easily accessible racemic 1-chloro-1-alkanol esters with aryl/vinyl electrophiles. The method features a broad substrate scope...

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Detalles Bibliográficos
Autores principales: Sun, Deli, Tao, Xianghua, Ma, Guobin, Wang, Jifen, Chen, Yunrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297475/
https://www.ncbi.nlm.nih.gov/pubmed/35919724
http://dx.doi.org/10.1039/d2sc02806a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297475/
https://www.ncbi.nlm.nih.gov/pubmed/35919724
http://dx.doi.org/10.1039/d2sc02806a

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