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Anesthesia promotes acute expression of genes related to Alzheimer’s disease and latent tau aggregation in transgenic mouse models of tauopathy

BACKGROUND: Exposure to anesthesia in the elderly might increase the risk of dementia. Although the mechanism underlying the association is uncertain, anesthesia has been shown to induce acute tau hyperphosphorylation in preclinical models. We sought to investigate the impact of anesthesia on gene e...

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Detalles Bibliográficos
Autores principales:	Eun, John David, Jimenez, Heidy, Adrien, Leslie, Wolin, Adam, Marambaud, Philippe, Davies, Peter, Koppel, Jeremy L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297560/ https://www.ncbi.nlm.nih.gov/pubmed/35858831 http://dx.doi.org/10.1186/s10020-022-00506-4

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