Mesenchymal stem cell-derived exosomes protect against liver fibrosis via delivering miR-148a to target KLF6/STAT3 pathway in macrophages

BACKGROUND: Despite emerging evidence on the therapeutic potential of mesenchymal stem cells (MSCs) for liver fibrosis, the underlying mechanisms remain unclear. At present, MSC-derived exosomes (MSC-EXOs) are widely accepted as crucial messengers for intercellular communication. This study aimed to...

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Detalles Bibliográficos
Autores principales: Tian, Siyuan, Zhou, Xia, Zhang, Miao, Cui, Lina, Li, Bo, Liu, Yansheng, Su, Rui, Sun, Keshuai, Hu, Yinan, Yang, Fangfang, Xuan, Guoyun, Ma, Shuoyi, Zheng, Xiaohong, Zhou, Xinmin, Guo, Changcun, Shang, Yulong, Wang, Jingbo, Han, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297598/
https://www.ncbi.nlm.nih.gov/pubmed/35858897
http://dx.doi.org/10.1186/s13287-022-03010-y

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