Co-delivery of carbonic anhydrase IX inhibitor and doxorubicin as a promising approach to address hypoxia-induced chemoresistance

Hypoxia, an oxygen-deprived condition of the tumor, is one of the major reasons for resistance to chemotherapy. Carbonic anhydrases are generally involved in pH homeostasis in normal conditions, but in solid tumors having a strong relation with hypoxia, the carbonic anhydrase IX (CA-IX) enzyme is ov...

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Detalles Bibliográficos
Autores principales: Amin, Muhammad Umair, Ali, Sajid, Ali, Muhammad Yasir, Fuhrmann, Dominik C., Tariq, Imran, Seitz, Benjamin S., Preis, Eduard, Brüßler, Jana, Brüne, Bernhard, Bakowsky, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297722/
https://www.ncbi.nlm.nih.gov/pubmed/35848469
http://dx.doi.org/10.1080/10717544.2022.2092234

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