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Shape Memory Alloy Helical Microrobots with Transformable Capability towards Vascular Occlusion Treatment

Practical implementation of minimally invasive biomedical applications has been a long-sought goal for microrobots. In this field, most previous studies only demonstrate microrobots with locomotion ability or performing a single task, unable to be functionalized effectively. Here, we propose a bioco...

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Detalles Bibliográficos
Autores principales: Zhang, Hehua, Xu, Borui, Ouyang, Yi, Wang, Yunqi, Zhu, Hong, Huang, Gaoshan, Cui, Jizhai, Mei, Yongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297727/
https://www.ncbi.nlm.nih.gov/pubmed/35928304
http://dx.doi.org/10.34133/2022/9842752
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author Zhang, Hehua
Xu, Borui
Ouyang, Yi
Wang, Yunqi
Zhu, Hong
Huang, Gaoshan
Cui, Jizhai
Mei, Yongfeng
author_facet Zhang, Hehua
Xu, Borui
Ouyang, Yi
Wang, Yunqi
Zhu, Hong
Huang, Gaoshan
Cui, Jizhai
Mei, Yongfeng
author_sort Zhang, Hehua
collection PubMed
description Practical implementation of minimally invasive biomedical applications has been a long-sought goal for microrobots. In this field, most previous studies only demonstrate microrobots with locomotion ability or performing a single task, unable to be functionalized effectively. Here, we propose a biocompatible shape memory alloy helical microrobot with regulative structure transformation, making it possible to adjust its motion behavior and mechanical properties precisely. Especially, towards vascular occlusion problem, these microrobots reveal a fundamental solution strategy in the mechanical capability using shape memory effect. Such shape-transformable microrobots can not only manipulate thrust and torque by structure to enhance the unclogging efficiency as a microdriller but also utilize the high work energy to apply the expandable helical tail as a self-propulsive stent. The strategy takes advantage of untethered manipulation to operate microsurgery without unnecessary damage. This study opens a route to functionalize microrobots via accurate tuning in structures, motions, and mechanical properties.
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spelling pubmed-92977272022-08-03 Shape Memory Alloy Helical Microrobots with Transformable Capability towards Vascular Occlusion Treatment Zhang, Hehua Xu, Borui Ouyang, Yi Wang, Yunqi Zhu, Hong Huang, Gaoshan Cui, Jizhai Mei, Yongfeng Research (Wash D C) Research Article Practical implementation of minimally invasive biomedical applications has been a long-sought goal for microrobots. In this field, most previous studies only demonstrate microrobots with locomotion ability or performing a single task, unable to be functionalized effectively. Here, we propose a biocompatible shape memory alloy helical microrobot with regulative structure transformation, making it possible to adjust its motion behavior and mechanical properties precisely. Especially, towards vascular occlusion problem, these microrobots reveal a fundamental solution strategy in the mechanical capability using shape memory effect. Such shape-transformable microrobots can not only manipulate thrust and torque by structure to enhance the unclogging efficiency as a microdriller but also utilize the high work energy to apply the expandable helical tail as a self-propulsive stent. The strategy takes advantage of untethered manipulation to operate microsurgery without unnecessary damage. This study opens a route to functionalize microrobots via accurate tuning in structures, motions, and mechanical properties. AAAS 2022-07-06 /pmc/articles/PMC9297727/ /pubmed/35928304 http://dx.doi.org/10.34133/2022/9842752 Text en Copyright © 2022 Hehua Zhang et al. https://creativecommons.org/licenses/by/4.0/Exclusive Licensee Science and Technology Review Publishing House. Distributed under a Creative Commons Attribution License (CC BY 4.0).
spellingShingle Research Article
Zhang, Hehua
Xu, Borui
Ouyang, Yi
Wang, Yunqi
Zhu, Hong
Huang, Gaoshan
Cui, Jizhai
Mei, Yongfeng
Shape Memory Alloy Helical Microrobots with Transformable Capability towards Vascular Occlusion Treatment
title Shape Memory Alloy Helical Microrobots with Transformable Capability towards Vascular Occlusion Treatment
title_full Shape Memory Alloy Helical Microrobots with Transformable Capability towards Vascular Occlusion Treatment
title_fullStr Shape Memory Alloy Helical Microrobots with Transformable Capability towards Vascular Occlusion Treatment
title_full_unstemmed Shape Memory Alloy Helical Microrobots with Transformable Capability towards Vascular Occlusion Treatment
title_short Shape Memory Alloy Helical Microrobots with Transformable Capability towards Vascular Occlusion Treatment
title_sort shape memory alloy helical microrobots with transformable capability towards vascular occlusion treatment
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297727/
https://www.ncbi.nlm.nih.gov/pubmed/35928304
http://dx.doi.org/10.34133/2022/9842752
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