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Features of ophthalmic, magnetic resonance imaging, and histopathology of a feline case of idiopathic sclerosing orbital pseudotumor

In the present report, we describe a case of sclerosing orbital pseudotumor in an 11‐year‐old castrated male American Shorthair cat. Ophthalmic exam showed lagophthalmos, retracted right upper eyelid, and resistant to retropulsion in his right eye. Under magnetic resonance imaging (MRI) scans, incre...

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Autores principales: Lee, Hao, Wu, Chih‐Ching, Liao, Pei‐Wen, Michael Chang, Kunbee, Wei, Li‐Ning, Wu, Yi‐Ying, Chan, Man‐Ha, Chiang, Yi‐Shan, Pang, Victor Fei, Lin, Chung‐Tien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297745/
https://www.ncbi.nlm.nih.gov/pubmed/35506154
http://dx.doi.org/10.1002/vms3.822
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author Lee, Hao
Wu, Chih‐Ching
Liao, Pei‐Wen
Michael Chang, Kunbee
Wei, Li‐Ning
Wu, Yi‐Ying
Chan, Man‐Ha
Chiang, Yi‐Shan
Pang, Victor Fei
Lin, Chung‐Tien
author_facet Lee, Hao
Wu, Chih‐Ching
Liao, Pei‐Wen
Michael Chang, Kunbee
Wei, Li‐Ning
Wu, Yi‐Ying
Chan, Man‐Ha
Chiang, Yi‐Shan
Pang, Victor Fei
Lin, Chung‐Tien
author_sort Lee, Hao
collection PubMed
description In the present report, we describe a case of sclerosing orbital pseudotumor in an 11‐year‐old castrated male American Shorthair cat. Ophthalmic exam showed lagophthalmos, retracted right upper eyelid, and resistant to retropulsion in his right eye. Under magnetic resonance imaging (MRI) scans, increased volume of the extraocular muscles (EOMs) of the right eye was prominent. Immunosuppressive dosage of prednisolone partially ameliorated the clinical signs, but some clinical signs were still gradually progressive or persistent. In the second MRI scan, decreased diameter of the thickened right extraocular muscles was found. After the third MRI scan, enucleation of the right eye was performed due to substantial adverse effects of systemic steroid therapy. Histopathological examination revealed no evidence of neoplastic transformation nor infection. Feline restrictive orbital myofibroblastic sarcoma (FROMS) was therefore excluded, suggesting unknown causes of extensive fibrotic changes in the right orbit of the affected cat.
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spelling pubmed-92977452022-07-22 Features of ophthalmic, magnetic resonance imaging, and histopathology of a feline case of idiopathic sclerosing orbital pseudotumor Lee, Hao Wu, Chih‐Ching Liao, Pei‐Wen Michael Chang, Kunbee Wei, Li‐Ning Wu, Yi‐Ying Chan, Man‐Ha Chiang, Yi‐Shan Pang, Victor Fei Lin, Chung‐Tien Vet Med Sci CATS In the present report, we describe a case of sclerosing orbital pseudotumor in an 11‐year‐old castrated male American Shorthair cat. Ophthalmic exam showed lagophthalmos, retracted right upper eyelid, and resistant to retropulsion in his right eye. Under magnetic resonance imaging (MRI) scans, increased volume of the extraocular muscles (EOMs) of the right eye was prominent. Immunosuppressive dosage of prednisolone partially ameliorated the clinical signs, but some clinical signs were still gradually progressive or persistent. In the second MRI scan, decreased diameter of the thickened right extraocular muscles was found. After the third MRI scan, enucleation of the right eye was performed due to substantial adverse effects of systemic steroid therapy. Histopathological examination revealed no evidence of neoplastic transformation nor infection. Feline restrictive orbital myofibroblastic sarcoma (FROMS) was therefore excluded, suggesting unknown causes of extensive fibrotic changes in the right orbit of the affected cat. John Wiley and Sons Inc. 2022-05-03 /pmc/articles/PMC9297745/ /pubmed/35506154 http://dx.doi.org/10.1002/vms3.822 Text en © 2022 The Authors. Veterinary Medicine and Science published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle CATS
Lee, Hao
Wu, Chih‐Ching
Liao, Pei‐Wen
Michael Chang, Kunbee
Wei, Li‐Ning
Wu, Yi‐Ying
Chan, Man‐Ha
Chiang, Yi‐Shan
Pang, Victor Fei
Lin, Chung‐Tien
Features of ophthalmic, magnetic resonance imaging, and histopathology of a feline case of idiopathic sclerosing orbital pseudotumor
title Features of ophthalmic, magnetic resonance imaging, and histopathology of a feline case of idiopathic sclerosing orbital pseudotumor
title_full Features of ophthalmic, magnetic resonance imaging, and histopathology of a feline case of idiopathic sclerosing orbital pseudotumor
title_fullStr Features of ophthalmic, magnetic resonance imaging, and histopathology of a feline case of idiopathic sclerosing orbital pseudotumor
title_full_unstemmed Features of ophthalmic, magnetic resonance imaging, and histopathology of a feline case of idiopathic sclerosing orbital pseudotumor
title_short Features of ophthalmic, magnetic resonance imaging, and histopathology of a feline case of idiopathic sclerosing orbital pseudotumor
title_sort features of ophthalmic, magnetic resonance imaging, and histopathology of a feline case of idiopathic sclerosing orbital pseudotumor
topic CATS
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297745/
https://www.ncbi.nlm.nih.gov/pubmed/35506154
http://dx.doi.org/10.1002/vms3.822
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