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Vandetanib drives growth arrest and promotes sensitivity to imatinib in chronic myeloid leukemia by targeting ephrin type‐B receptor 4

The oncogenic role of ephrin type‐B receptor 4 (EPHB4) has been reported in many types of tumors, including chronic myeloid leukemia (CML). Here, we found that CML patients have a higher EPHB4 expression level than healthy subjects. EPHB4 knockdown inhibited growth of K562 cells (a human immortalize...

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Detalles Bibliográficos
Autores principales: Ma, Weina, Zhu, Man, Wang, Bo, Gong, Zhengyan, Du, Xia, Yang, Tianfeng, Shi, Xianpeng, Dai, Bingling, Zhan, Yingzhuan, Zhang, Dongdong, Ji, Yanhong, Wang, Yang, Li, Song, Zhang, Yanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297786/
https://www.ncbi.nlm.nih.gov/pubmed/35689424
http://dx.doi.org/10.1002/1878-0261.13270