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Spinal epidural and synovial lipomatosis in a 3‐year‐old Eurasian dog receiving sustained steroid therapy

This report describes a spinal cord epidural and synovial lipomatosis in a 3‐year‐old neutered male Eurasian dog. This dog presented for ambulatory paraparesis and was previously treated with immunosuppressive dosages of prednisolone for 2 years. Computed tomography (CT) myelography and magnetic res...

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Detalles Bibliográficos
Autores principales: Signoret, Marion, Gros, Lucile, Dumont, Renaud, Dally, Claire, Le Boedec, Kevin, Cauzinille, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297791/
https://www.ncbi.nlm.nih.gov/pubmed/35732060
http://dx.doi.org/10.1002/vms3.842
Descripción
Sumario:This report describes a spinal cord epidural and synovial lipomatosis in a 3‐year‐old neutered male Eurasian dog. This dog presented for ambulatory paraparesis and was previously treated with immunosuppressive dosages of prednisolone for 2 years. Computed tomography (CT) myelography and magnetic resonnance imaging (MRI) images identified dorsal compression of the thoraco‐lumbar spinal cord by hypertrophic epidural fat. Histological examination identified extensive well‐differentiated mature adipose tissue in the subepithelial area of the tarsal synovium. Prednisolone is a reported predisposing factor in humans with lipomatosis.