Spinal epidural and synovial lipomatosis in a 3‐year‐old Eurasian dog receiving sustained steroid therapy

This report describes a spinal cord epidural and synovial lipomatosis in a 3‐year‐old neutered male Eurasian dog. This dog presented for ambulatory paraparesis and was previously treated with immunosuppressive dosages of prednisolone for 2 years. Computed tomography (CT) myelography and magnetic res...

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Autores principales: Signoret, Marion, Gros, Lucile, Dumont, Renaud, Dally, Claire, Le Boedec, Kevin, Cauzinille, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
DOGS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297791/
https://www.ncbi.nlm.nih.gov/pubmed/35732060
http://dx.doi.org/10.1002/vms3.842
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author Signoret, Marion
Gros, Lucile
Dumont, Renaud
Dally, Claire
Le Boedec, Kevin
Cauzinille, Laurent
author_facet Signoret, Marion
Gros, Lucile
Dumont, Renaud
Dally, Claire
Le Boedec, Kevin
Cauzinille, Laurent
author_sort Signoret, Marion
collection PubMed
description This report describes a spinal cord epidural and synovial lipomatosis in a 3‐year‐old neutered male Eurasian dog. This dog presented for ambulatory paraparesis and was previously treated with immunosuppressive dosages of prednisolone for 2 years. Computed tomography (CT) myelography and magnetic resonnance imaging (MRI) images identified dorsal compression of the thoraco‐lumbar spinal cord by hypertrophic epidural fat. Histological examination identified extensive well‐differentiated mature adipose tissue in the subepithelial area of the tarsal synovium. Prednisolone is a reported predisposing factor in humans with lipomatosis.
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spelling pubmed-92977912022-07-22 Spinal epidural and synovial lipomatosis in a 3‐year‐old Eurasian dog receiving sustained steroid therapy Signoret, Marion Gros, Lucile Dumont, Renaud Dally, Claire Le Boedec, Kevin Cauzinille, Laurent Vet Med Sci DOGS This report describes a spinal cord epidural and synovial lipomatosis in a 3‐year‐old neutered male Eurasian dog. This dog presented for ambulatory paraparesis and was previously treated with immunosuppressive dosages of prednisolone for 2 years. Computed tomography (CT) myelography and magnetic resonnance imaging (MRI) images identified dorsal compression of the thoraco‐lumbar spinal cord by hypertrophic epidural fat. Histological examination identified extensive well‐differentiated mature adipose tissue in the subepithelial area of the tarsal synovium. Prednisolone is a reported predisposing factor in humans with lipomatosis. John Wiley and Sons Inc. 2022-06-22 /pmc/articles/PMC9297791/ /pubmed/35732060 http://dx.doi.org/10.1002/vms3.842 Text en © 2022 The Authors. Veterinary Medicine and Science published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle DOGS
Signoret, Marion
Gros, Lucile
Dumont, Renaud
Dally, Claire
Le Boedec, Kevin
Cauzinille, Laurent
Spinal epidural and synovial lipomatosis in a 3‐year‐old Eurasian dog receiving sustained steroid therapy
title Spinal epidural and synovial lipomatosis in a 3‐year‐old Eurasian dog receiving sustained steroid therapy
title_full Spinal epidural and synovial lipomatosis in a 3‐year‐old Eurasian dog receiving sustained steroid therapy
title_fullStr Spinal epidural and synovial lipomatosis in a 3‐year‐old Eurasian dog receiving sustained steroid therapy
title_full_unstemmed Spinal epidural and synovial lipomatosis in a 3‐year‐old Eurasian dog receiving sustained steroid therapy
title_short Spinal epidural and synovial lipomatosis in a 3‐year‐old Eurasian dog receiving sustained steroid therapy
title_sort spinal epidural and synovial lipomatosis in a 3‐year‐old eurasian dog receiving sustained steroid therapy
topic DOGS
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297791/
https://www.ncbi.nlm.nih.gov/pubmed/35732060
http://dx.doi.org/10.1002/vms3.842
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